Bioavailability and pharmacokinetics of oral meloxicam in llamas

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Bioavailability and pharmacokinetics of oral meloxicam in llamas

BACKGROUND South American camelids in the United States have rapidly developed into an important agricultural industry in need of veterinary services. Pain management is challenging in camelids because there are no drugs currently approved by the U.S. Food and Drug Administration for use in these species. Dosage regimens used for many therapeutic drugs have been extrapolated from other ruminant...

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Oral pharmacokinetics of fenbendazole in llamas, South American Camelids.

Llamas, South American Camelids are increasingly popular in the United States, as a source of fiber, livestock guard, and pack animals. Gastrointestinal parasites have been identified as a major health problem in all classes of livestock including llamas. Currently, there are no approved anthelmintics available for use in llamas. In this study, the pharmacokinetics of a single, oral administrat...

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Absolute Bioavailability of Oral Meloxicam in Healthy Dogs

Meloxicam, a non-steroidal anti-Inflammatory drug has been registered in Pakistan as a safe substitute of diclofenac sodium which was banned for veterinary use, due to its relay toxicity associated with the catastrophic decline in vulture population of the Indian subcontinent. In Pakistan, Injection is the only dosage form registered for veterinary purposes whereas Boehringer Ingelheim are lice...

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Pharmacokinetics of intravenous and intramuscular tramadol in llamas.

The purpose of this study was to determine the pharmacokinetics of tramadol and its metabolite M1 after intravenous and intramuscular administration to llamas. Tramadol, a centrally acting analgesic whose efficacy is a result of complex interactions between opiate, adrenergic and serotonin receptor systems, has been used clinically to treat moderate to severe pain in humans. The pharmacokinetic...

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Pharmacokinetics of Meloxicam in Healthy Donkeys

Meloxicam, a non-steroidal anti-Inflammatory drug (NSAID), has been reported as a safe substitute for diclofenac which was banned for veterinary use during 2005-06, due to its relay toxicity associated with the catastrophic decline in vulture populations in Indian subcontinent. It is a preferential cyclooxygenase-2 (COX-2) inhibiter with higher therapeutic index as compared to diclofenac, indom...

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ژورنال

عنوان ژورنال: BMC Veterinary Research

سال: 2012

ISSN: 1746-6148

DOI: 10.1186/1746-6148-8-85